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Sclerotherapy has long been the standard of care when treating cosmetic vein issues like spider veins and small varicose veins. Sclerotherapy involves treating the varicose veins by injecting chemicals that cause an injury to the inner lining of the vein resulting in closure of the vein. When treating the veins for cosmetic reasons, patients often find that their legs also feel better. Sclerotherapy can also be used to treat deeper, larger vessels with the guidance of ultrasound imaging. Sclerotherapy is most often used as an adjunct treatment after closure of larger feeder vessels by the laser. It is very important that these feeder vessels are treated first if you want the best possible results.